Dr. Vaibhav Sinha

Educator, Researcher, Administrator and Entrepreneur


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Determination of minor and trace elements in kidney stones by x-ray fluorescence analysis


Journal article


A. Srivastava, Brianne J. Heisinger, Vaibhav Sinha, Hyong-Koo Lee, Xin Liu, M. Qu, X. Duan, S. Leng, C. McCollough
Medical Imaging, 2014

Semantic Scholar DOI
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APA   Click to copy
Srivastava, A., Heisinger, B. J., Sinha, V., Lee, H.-K., Liu, X., Qu, M., … McCollough, C. (2014). Determination of minor and trace elements in kidney stones by x-ray fluorescence analysis. Medical Imaging.


Chicago/Turabian   Click to copy
Srivastava, A., Brianne J. Heisinger, Vaibhav Sinha, Hyong-Koo Lee, Xin Liu, M. Qu, X. Duan, S. Leng, and C. McCollough. “Determination of Minor and Trace Elements in Kidney Stones by x-Ray Fluorescence Analysis.” Medical Imaging (2014).


MLA   Click to copy
Srivastava, A., et al. “Determination of Minor and Trace Elements in Kidney Stones by x-Ray Fluorescence Analysis.” Medical Imaging, 2014.


BibTeX   Click to copy

@article{a2014a,
  title = {Determination of minor and trace elements in kidney stones by x-ray fluorescence analysis},
  year = {2014},
  journal = {Medical Imaging},
  author = {Srivastava, A. and Heisinger, Brianne J. and Sinha, Vaibhav and Lee, Hyong-Koo and Liu, Xin and Qu, M. and Duan, X. and Leng, S. and McCollough, C.}
}

Abstract

The determination of accurate material composition of a kidney stone is crucial for understanding the formation of the kidney stone as well as for preventive therapeutic strategies. Radiations probing instrumental activation analysis techniques are excellent tools for identification of involved materials present in the kidney stone. In particular, x-ray fluorescence (XRF) can be very useful for the determination of minor and trace materials in the kidney stone. The X-ray fluorescence measurements were performed at the Radiation Measurements and Spectroscopy Laboratory (RMSL) of department of nuclear engineering of Missouri University of Science and Technology and different kidney stones were acquired from the Mayo Clinic, Rochester, Minnesota. Presently, experimental studies in conjunction with analytical techniques were used to determine the exact composition of the kidney stone. A new type of experimental set-up was developed and utilized for XRF analysis of the kidney stone. The correlation of applied radiation source intensity, emission of X-ray spectrum from involving elements and absorption coefficient characteristics were analyzed. To verify the experimental results with analytical calculation, several sets of kidney stones were analyzed using XRF technique. The elements which were identified from this techniques are Silver (Ag), Arsenic (As), Bromine (Br), Chromium (Cr), Copper (Cu), Gallium (Ga), Germanium (Ge), Molybdenum (Mo), Niobium (Nb), Rubidium (Rb), Selenium (Se), Strontium (Sr), Yttrium (Y), Zirconium (Zr). This paper presents a new approach for exact detection of accurate material composition of kidney stone materials using XRF instrumental activation analysis technique.


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